Formula Test Results

DERMA E knows that results matter. 

That’s why we use independent clinical and consumer tests to prove our natural products really work. On this page, you can read all about our test methodology and proof that our products perform. With DERMA E, rest assured you'll never sacrifice your health or your safety to get the skincare performance you want. 

Anti-Wrinkle regimen
Firming DMAE Moisturizer
Hydrating Eye Crème
Psorzema® Crème
Scalp Relief
Scar Gel
Soothing Cleanser
Stretch Mark Crème
Very Clear® regimen

HRIPT: Skin Safety

Our #1 priority is to protect the health of your skin with safe, superior quality natural products that perform beyond your expectations. 

To ensure our formulas are safe and suitable for all skin types, DERMA E products undergo independent sensitivity and irritation clinical testing called HRIPT (human repeat insult patch test). So no matter what your skin type is, you can trust DERMA E for skin-friendly, earth-friendly formulas that deliver real results. 

✓Clinically tested          ✓Sensitivity tested

✓Dermatologist tested  ✓Safety tested

✓Allergy tested             ✓Irritation tested

Anti-Wrinkle regimen

Reveal Visibly Younger, Smoother, More Refined Skin

We put the entire regimen of eight Anti-Wrinkle products to the test! Does the line really help reduce the look of wrinkles and other signs of aging? After 12 weeks of use, here’s what we found.   

Wrinkles and Sun-Damage Visibly Diminished:

•  29% decrease in skin discoloration
•  24% decrease in total wrinkle volume
•  22% decrease in total wrinkle area
•  13% decrease in wrinkle depth

Youthful Looking Skin Revealed:

•  93% reported visible improvement in dullness
•  90% reported visible improvement in skin texture
•  90% reported visible improvement in roughness
•  84% reported visible improvement in lines and wrinkles



Firming DMAE Moisturizer

The Skin-Firming Secret is Out!

In an eight-week independent clinical test, Firming DMAE Moisturizer was proven to be just as effective as Perricone MD® Face Finishing Moisturizer at visibly improving skin firmness, elasticity and hydration.

The Firming DMAE Moisturizer and Perricone MD® Face Finishing Moisturizer formulas were entered into an independent, double-blind clinical test among 55 women aged 37 to 65. The study was conducted among 55 women aged 37 to 65. It was a split-face, double-blind test; one formula was applied on the entire left side and the other formula on the entire right side of the face simultaneously. Determination of left versus right application was randomly assigned. Formulas were ‘blinded’ so that neither the study participants nor the clinical technicians were aware of the brands being tested but could identify them by a specific code.

Results were measured by Corneometer and Cutometer devices at time points zero, four weeks and eight weeks. Participants also completed post-treatment comprehensive questionnaires.

Both quantitative and qualitative test results conclude that DERMA E Firming DMAE Moisturizer is as effective as Perricone MD® Face Finishing Moisturizer at visibly improving skin firmness, elasticity and hydration after eight weeks of use. 

DERMA E Firming DMAE Moisturizer Results After 8 Weeks of Use:

• 100% demonstrated increased skin hydration
• 87% demonstrated increased skin firmness
• 76% reported skin felt more resilient
• 76% reported skin looked more toned
• 75% reported skin looked more lifted

Participant Reviews of DERMA E Firming DMAE Moisturizer:

“Like an extended facelift”
“Really helped lift, tone and remove wrinkles”
“My face looked clearer, smooth, brighter, hydrated”
“My skin has a smooth baby soft feel with less aging lines”
“It makes my skin glow”


Hydrating Eye Crème

See Younger, Smoother Results

We put our best-selling eye crème to the test!

Does Hydrating Eye Crème really conquer dryness, fine lines, wrinkles and crow’s feet? Here’s what we found.

Results Measured After 12 Weeks of Use:

• 30% decrease in total wrinkle volume
• 26% decrease in total wrinkle area
• 15% decrease in total wrinkle depth


Signs of Aging Fade from Sight:

• 97% reported visible improvement in deep wrinkles
• 86% reported visible improvement in sagging
• 83% reported visible improvement in puffiness


Psorzema® Crème

Spread the Word!

Psorzema® Crème is clinically proven to significantly diminish symptoms of eczema and psoriasis.   

Proven Results:

In an independent clinical test, DERMA E Psorzema® Crème was proven to significantly improve symptoms of eczema and psoriasis after only 4 weeks of regular use. And after 8 weeks, the results just kept getting better:  

Soothing Satisfaction:

Aside from experiencing eczema and psoriasis symptom relief, participants were pleased with the overall feel and look of their skin.

• 96% felt very moisturizing
• 92% felt soothing upon application
• 88% helped skin look healthier
• 72% helped relieve itching 



Scalp Relief Shampoo and Conditioner

Target Dandruff Symptoms, Naturally

Scalp Relief Shampoo & Conditioner make a dramatic difference in dandruff symptoms.


Scar Gel

A Natural Cure for Scars?

In an independent clinical test, DERMA E Scar Gel was proven to significantly improve the look and feel of scars after only 4 weeks of regular use. And after 8 weeks, the results just kept getting better.

Proven Results:


% Showing

Significant Improvement


4 weeks

8 weeks

  Scar texture / smoothness



  Scar overall appearance



  Scar color










Rave Reviews:

DERMA E Scar Gel… % Participants Who Agree
Felt very moisturizing 100%
Had a smooth texture 100%
Was invisible on skin 100%
Was easy to use 100%




Soothing Cleanser

Cleanse Away Signs of Sensitivity

We tested the Soothing Cleanser among subjects with red, highly sensitive, easily irritated, rosacea-prone skin. After just one week of use, here’s what we found:

Goodbye Redness and Irritation:

• 85% of subjects reported reduced redness
• 92% of subjects reported less irritation

Hello Clean, Soft, Soothed Skin:

• 97% reported effective removal of makeup
• 95% reported soothed skin
• 95% reported soft skin




Stretch Mark Crème

Smooth Away Stretch Marks, Naturally

In an 8-week consumer test, DERMA E Stretch Mark Crème was shown to significantly diminished the look of stretch marks, improving texture, color and overall appearance.

Visibly Diminishes Stretch Marks:

• 82% reported improved texture / smoothness
• 73% reported improved color
• 73% reported improved overall appearance

Reconditions Skin:

• 100% felt fully moisturized
• 92% felt softer
• 82% looked smoother

Participants agreed…DERMA E Stretch Mark Crème delivered real results:

“Smelled great, not greasy, helped fade the mark a lot!”
 “It helped fade the discoloration of my stretch marks”
“Felt great on my skin; very smooth and moisturizing”

Very Clear® regimen

The Results are Clear...Very Clear®!

Results were noticeable within 7-10 days:

•  96% saw a reduction in blemishes and acne
•  93% saw a reduction in oil production
•  89% saw a reduction in redness
•  93% saw an improvement in overall skin health

Additionally, 93% would use the products again