The image shows a bottle of DERMA‑E Anti‑Aging Regenerative Serum in a sleek red container with a matte finish.
DERMA‑E Anti‑Aging Regenerative Serum displayed beside text reading “Retinol Without Irritation!” on a pink‑to‑white gradient background. The callouts list product benefits, including reducing the appearance of fine lines and wrinkles, gently removing dead skin cells, promoting the renewal of healthier cells, and protecting against free radicals and photoaging. A small arrow at the top notes that this is a limited‑edition size.
A clinical results graphic shows before‑and‑after close‑ups of the eye area over six weeks. The text above states, “97% saw reduced fine lines and wrinkles*,” with dotted circles highlighting the improvement.Before and after 6 weeks comparison of fine lines and wrinkles on skin with text claiming clinical results.
A bright informational graphic highlights key ingredients in the serum. It lists retinol for preventing and correcting lines and wrinkles, bakuchiol for enhancing retinol’s benefits, glycolic acid for promoting renewal of healthier skin cells, and avocado, sesame, and sunflower seed oils for keeping the skin soft, smooth, and supple.
The image displays two DERMA‑E serums side by side on a gradient background. The left bottle is a Vitamin C serum labeled “Morning Radiance,” while the right bottle is the Anti‑Aging Regenerative Serum with retinol and bakuchiol, labeled “Nighttime Wrinkle Defense.” Icons of a sun and a moon reinforce morning and night use, highlighting a complete day‑and‑night skincare routine.
A five‑star review graphic appears on a warm red gradient background. Below the stars, text reads: “Love this serum. I’ve actually seen a big change in my skin after a couple weeks.” — Mary. The layout highlights customer satisfaction and visible improvement.
This comparison image shows the new limited‑edition size of the DERMA‑E Anti‑Aging Regenerative Serum next to the original bottle. The larger new size is marked with a handwritten‑style “NEW!” arrow.
Close-up of a smooth, beige surface with a glossy finish.
The image shows a bottle of DERMA‑E Anti‑Aging Regenerative Serum in a sleek red container with a matte finish.
DERMA‑E Anti‑Aging Regenerative Serum displayed beside text reading “Retinol Without Irritation!” on a pink‑to‑white gradient background. The callouts list product benefits, including reducing the appearance of fine lines and wrinkles, gently removing dead skin cells, promoting the renewal of healthier cells, and protecting against free radicals and photoaging. A small arrow at the top notes that this is a limited‑edition size.
A clinical results graphic shows before‑and‑after close‑ups of the eye area over six weeks. The text above states, “97% saw reduced fine lines and wrinkles*,” with dotted circles highlighting the improvement.Before and after 6 weeks comparison of fine lines and wrinkles on skin with text claiming clinical results.
A bright informational graphic highlights key ingredients in the serum. It lists retinol for preventing and correcting lines and wrinkles, bakuchiol for enhancing retinol’s benefits, glycolic acid for promoting renewal of healthier skin cells, and avocado, sesame, and sunflower seed oils for keeping the skin soft, smooth, and supple.
The image displays two DERMA‑E serums side by side on a gradient background. The left bottle is a Vitamin C serum labeled “Morning Radiance,” while the right bottle is the Anti‑Aging Regenerative Serum with retinol and bakuchiol, labeled “Nighttime Wrinkle Defense.” Icons of a sun and a moon reinforce morning and night use, highlighting a complete day‑and‑night skincare routine.
A five‑star review graphic appears on a warm red gradient background. Below the stars, text reads: “Love this serum. I’ve actually seen a big change in my skin after a couple weeks.” — Mary. The layout highlights customer satisfaction and visible improvement.
This comparison image shows the new limited‑edition size of the DERMA‑E Anti‑Aging Regenerative Serum next to the original bottle. The larger new size is marked with a handwritten‑style “NEW!” arrow.
Close-up of a smooth, beige surface with a glossy finish.

Anti-Aging Regenerative Serum, Limited Edition (1.7 oz)

Fight fine lines and wrinkles with a proprietary blend of non-irritating Retinol + Bakuchiol
$23.95 Sale • Save
FREE SHIPPING WITH PURCHASE $55+  FREE SHIPPING WITH PURCHASE $55+ 
45 Days Money Back Guarantee 45 Days Money Back Guarantee

Anti-Aging Regenerative Serum (1.7 oz) is a powerful yet gentle solution for addressing fine lines and wrinkles. Formulated with a synergistic blend of Retinol, Bakuchiol, and Glycolic Acid, it targets signs of aging while remaining gentle on sensitive skin.

  • Gently exfoliates and promotes healthy cell renewal without visible irritation or redness.
  • Fights signs of aging and diminishes the appearance of fine lines and wrinkles.
  • Helps keep skin soft and smooth for a radiant, healthier-looking complexion.

Recommended for use in nighttime routines. Start by using 1 to 2 times a week, then gradually increase frequency to nightly use. After cleansing, apply a small amount of serum to your dry face and neck and allow it to absorb. Use alone or with your favorite DERMA E moisturizer.

  • Retinol: helps minimize the appearance of fine lines and wrinkles for a fresher, younger appearance
  • Bakuchiol: boosts Retinol’s effectiveness; helps reduce visible signs of irritation and redness.
  • Glycolic Acid: helps exfoliate to safely remove dead surface skin cells.
  • Vitamin E: an antioxidant that helps nourish and improve the appearance of skin's texture.
  • Green Tea Extract: protects against everyday stressors.
  • Avocado, Sesame & Sunflower Seed Oils: leave skin soft, smooth, and supple.

Purified Water, Glycerin (Vegetable Derived), Coco-Caprylate (Coconut Derived), Xanthan Gum, Capryloyl Glycerin/Sebacic Acid Copolymer, Diheptyl Succinate, Camellia Sinensis (Green Tea) CO Leaf Extract, Tocopheryl Acetate (Vitamin E), Retinol, Bakuchiol, Panthenol (Provitamin B5), Glyceryl Stearate (Vegetable Derived), Glyceryl Stearate Citrate (Vegetable Derived), Potassium Cetyl Phosphate, Glycolic Acid, Sodium Hydroxide, Lavandula Angustifolia (Lavender) Oil, Helianthus Annuus (Sunflower) Seed Oil, Persea Gratissima (Avocado) Oil, Sesamum Indicum (Sesame) Seed Oil, Polysorbate 20, Salvia Officinalis (Sage) Oil, Beta-Caryophyllene, Eucalyptol, Orange Terpenes, Alpha Pinene, Camphor, Citral, Geranyl Acetate, Mentha Viridis (Spearmint) Leaf Oil, Citronellal, Phenoxyethanol, Ethylhexylglycerin.

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All of DERMA E’s anti-wrinkle products harness the power of Vitamin A. Its effect on the complexion is so potent that it is also known as the “skin vitamin”—it can smooth the look of lines and improve the tone and texture of the skin’s surface.

While the Vitamin A in the Anti-Wrinkle collection encourages fresh-looking skin, it is supported by antioxidants such as green tea and Vitamin E to help protect the surface layer of the skin from free radical damage. This combination of ingredients refreshes the complexion—you look renewed and revived.

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